Neurobiology of Sleep-Wake Control

Cho, Yong-Won

doi:2006.3.1.6

J Korean Sleep Res Soc > Volume 3(1); 2006 > Article

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J Korean Sleep Res Soc. 2006;3(1):6-10. doi: https://doi.org/10.13078/jksrs.06002

수면 각성 조절의 신경생물학

조용원

계명대학교 신경과

Neurobiology of Sleep-Wake Control

Yong-Won Cho

Department of Neurology, College of Medicine, Keimyung University, Daegu, Korea

Corresponding Author: Yong-Won Cho ,Tel: +82-53-250-7831, Fax: +82-53-250-7840, Email: neurocho@dsmc.or.kr

Received: May 1, 2006 Accepted: May 19, 2006 Published online: June 30, 2006

ABSTRACT

The regulations of sleep-wake cycle is complicated and many neurochemicals are involved. It is the consequence of an active process requiring appropriate interactions ofbrainstem and the cerebral system. The homeostatic drive and circadian factors are major controls in this regulation. The reticular activation system is a wake promoting area and the neurons in pons and preoptic areas are involved in non-rapid eye movement sleep and rapid eye movement sleep. Sleep is a necessary behavior and it is, at least in part, a restorative process. Good sleep during the nightis important for a healthy condition during the day time. Understanding of these reciprocal sleep-wake interactions should be very important to better understand the effects of many drugs and many other sleep related diseases.

Keywords: sleep | arousal | neurobiology