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J Korean Sleep Res Soc > Volume 5(1); 2008 > Article
J Korean Sleep Res Soc. 2008;5(1):17-25.         doi: https://doi.org/10.13078/jksrs.08003
Central Sleep Apnea in Heart Failure: Clinical Implications,Recognition, and Management
Central Sleep Apnea in Heart Failure: Clinical Implications,Recognition, and Management
Chang-Ho Yun
Department of Neurology, College of Medicine, Inha University, Incheon, Korea
Corresponding Author: Chang-Ho Yun ,Tel: +82-32-890-3418, 386, Fax: +82-32-890-3864, Email: ych333@chol.com/ych333@inha.ac.kr
Received: June 11, 2008   Accepted: June 25, 2008   Published online: June 30, 2008
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Central sleep apnea (CSA) is characterized by a lack of respiratory drive during sleep, resulting in repetitive periods of insufficient ventilation and compromised gas exchange. These nighttime breathing disturbances can lead to daytime impairment and poor cardiovascular outcomes. There are several types of CSA, including idiopathic CSA, high altitude-induced periodic breathing, obesity hypoventilation syndrome, drug-induced central apnea, and Cheyne-Stokes breathing pattern. While unstable ventilatory control during sleep is the hallmark of CSA, the pathophysiology and the prevalence of the various forms of CSA varies greatly. Among them, CSA associated with heart failure is well-studied in the respect of clinical impact and management strategy. Through this article, I will summarize the underlying pathophysiology, clinical impacts, and potential treatment of CSA occurring in subjects with heart failure.
Keywords: Sleep disorderd breathing | Pathophysiology | Cheyne-Stokes respiration | Continuous positive airway pressure
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